01
Glucosamine Sulfate
Cartilage Building Block
Glucosamine Sulfate is the foundational raw material that the body uses to build and maintain articular cartilage. NIH-funded clinical research including the landmark GAIT trial has studied glucosamine's role in joint health extensively. As the body's natural glucosamine production declines with age, cartilage receives insufficient structural support, and supplementation provides the specific molecular building block cartilage needs. In AMP Joint 10, Glucosamine Sulfate is the cartilage nutrition foundation on which the rest of the formula builds.
02
Chondroitin Sulfate
Cartilage Hydration and Shock Absorption
Chondroitin Sulfate is the glycosaminoglycan that gives cartilage its water-attracting, shock-absorbing properties. Working synergistically with Glucosamine as a complementary pair also studied in the GAIT trial, Chondroitin maintains the hydration status and compression resistance of cartilage, supporting the cartilage's ability to cushion joints during movement and distribute force effectively across its surface.
03
MSM
Methylsulfonylmethane • Organic Sulfur
MSM provides the organic sulfur that joints, tendons and ligaments need for ongoing connective tissue synthesis and maintenance. Sulfur is a mineral required for collagen and glycosaminoglycan production, making MSM essential for joint structural maintenance. Beyond its structural role, MSM has been documented in published randomized controlled trials for its anti-inflammatory effects and its support of joint comfort and physical function.
04
Boswellia Serrata Extract
Leukotriene Inhibitor • Multiple Clinical Trials
Boswellia Serrata's active boswellic acids, particularly AKBA, inhibit 5-lipoxygenase and the leukotriene production this enzyme drives. Leukotrienes are potent inflammatory mediators that contribute directly to joint tissue breakdown and chronic discomfort. Multiple double-blind, placebo-controlled studies have documented Boswellia's effects on knee joint comfort, function and range of motion, with some trials showing measurable improvements within as little as 7 days.
05
Turmeric Curcumin
COX-2 Inhibitor • Arthritis Foundation Recognized
Turmeric Curcumin is one of the most extensively documented natural anti-inflammatory compounds available, recognized by the Arthritis Foundation in their published guidance on complementary joint health approaches. Curcumin inhibits COX-2, the enzyme that produces prostaglandins and drives joint inflammation. Its challenge has historically been bioavailability, which is why BioPerine is the next ingredient in the AMP Joint 10 formula.
06
BioPerine
Black Pepper Extract • Absorption Multiplier
BioPerine is a standardized black pepper extract containing 95% piperine, documented to increase curcumin bioavailability by up to 2000% in human subjects. Without BioPerine, curcumin passes through the gut largely unabsorbed. With BioPerine, it reaches joint tissue at concentrations that reflect its documented COX-2 inhibitory potency. BioPerine also enhances the absorption of several other AMP Joint 10 compounds, functioning as a formula-wide bioavailability optimizer.
07
Hyaluronic Acid
Synovial Fluid Lubrication • Joint Cushioning
Hyaluronic Acid is the primary structural component of synovial fluid, the viscous lubricating liquid that fills every movable joint capsule. HA provides both lubrication and shock absorption. As HA concentration in synovial fluid naturally declines with age, joints become less lubricated and impact-sensitive. Oral HA supplementation has been documented in published research to support improved joint lubrication and comfort, addressing the movement-smoothness dimension that structural and anti-inflammatory ingredients alone cannot target.
08
Collagen Type II
Articular Cartilage Integrity • Structural Protein
Collagen Type II is the predominant structural protein in articular cartilage, comprising approximately 90 to 95 percent of its total collagen content. Unlike Collagen Type I in skin and tendon, Type II collagen is specifically structured for cartilage's mechanical demands. Clinical research has documented undenatured Collagen Type II supplementation for joint comfort, stiffness and function. In AMP Joint 10, Collagen Type II complements Glucosamine and Chondroitin by addressing the fibrous protein framework of cartilage directly.
09
Quercetin
Antioxidant Flavonoid • Oxidative Stress Protection
Quercetin is a potent antioxidant flavonoid that addresses the oxidative stress dimension of joint degradation that anti-inflammatory compounds do not specifically target. Free radicals accumulate in joint tissue and directly damage cartilage matrix proteins and chondrocyte function, accelerating cartilage breakdown. Quercetin's documented antioxidant and anti-inflammatory activities make it an important protective component in AMP Joint 10's comprehensive approach to joint health maintenance.
10
Bromelain
Pineapple Enzyme • Inflammation Modulation
Bromelain is a proteolytic enzyme complex from pineapple stem documented for its effects on joint inflammation and swelling. As a proteolytic enzyme, Bromelain breaks down proteins in the inflammatory cascade, modulating pro-inflammatory compound accumulation in joint tissue. Published research in Clinical Rheumatology and related journals has studied Bromelain's effects on joint comfort. Bromelain also enhances absorption of other compounds, complementing BioPerine's bioavailability-supporting function in AMP Joint 10.
Formula10 clean ingredients, daily capsule
CleanNo gluten, dairy, sugar, artificial ingredients
Made inUSA, GMP-certified, registered facility
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